Fallopia aubertii (L. Henry) Holub A; Polygonum amphibium L. -> Persicaria amphibia (L.) Gray; Polygonum amplexicaule D. Don; Polygonum aubertii L. Henry s-> Fallopia aubertii (L. Henry) Holub A hypoleucum It is native to Central and southern China. When the genus is defined narrowly, Polygonum species are annual or perennial herbaceous plants, rarely shrubby, with much branched stems. Scientific Name(s): Polygonum multiflorum Thunb.Common Name(s): Chinese cornbind, Climbing knotweed, Flowery knotweed, Fo-ti, Heshouwu, Radix Polygoni multiflori, Tuber fleeceflower. Fallopia multiflora (Thunb.) Of the 217 supplement products implicated in liver injury, fo-ti was among the 22% (116) of the single-ingredient products.55, Reviews of the toxic effects, possibly dose- and duration-related, of P. multiflorum on the liver have been published. WHAT'S IN AN HERB NAME? It is probably best known for it’s ability to turn grey hair dark again. Prepare as a tea or tonic, or as directed by a physician. Emodin has demonstrated inhibitory effects on vasodilation in isolated rat aortas.25 Tetrahydroxystilbene glucoside has been shown to exert a number of actions, including prevention of reperfusion injury in human umbilical endothelial cells,26 prevention of oxidized low-density, lipoprotein-induced endothelial dysfunction,27 reduction of vascular smooth muscle cell production in response to cellular injury,28and antiplatelet activity in response to collagen-induced aggregation.29. A number of species that had been included in Polygonum have been moved into several other genera, including Bistorta, Fagopyrum, Fallopia, Koenigia, Persicaria and Reynoutria. He Shou Wu is a Chinese herbal medicine, derived from the Polygonum multiflorum Thunb plant ().. The roots are the main plant part of interest and are harvested and dried in autumn when they are 3 to 4 years of age, but the stems and leaves are also used. Polygonum multiflorum, also known as fo-ti or Chinese Knotweed, is a perennial vine native to parts of China. Liver transplant was also more frequent with toxicity from non-bodybuilding supplements (13%) than with conventional medications (3%) (P<0.001). Overall, the number of severe liver injury cases was significantly higher from supplements than conventional medications (P=0.02). This information is not specific medical advice and does not replace information you receive from your health care provider. The species Polygonatum multiflorum is often called the Common Solomon's Seal, native to Europe it has been long cultivated for its use as a medicinal herb. Suitable pH: acid, neutral and basic (alkaline) soils. Ho-shou-wu (pinyin: heshouwu) is derived from the roots of Polygonum multiflorum.The herb was first recorded (1,2,16) in the Ri Huazi Bencao (Tang Dynasty, 713 A.D.) and then incorporated into the well-known Kaibao Bencao (Song Dynasty; 973 A.D.). There are no clinical data regarding the use of P. multiflorum in cardiovascular-related disorders. Common Name: He Shou Wu. Care should be taken not to confuse Polygonum with Polygonatum – an entirely different genus of plants. Evidence of hepatic injury in humans exists; consider P. multiflorum and its extracts hepatotoxic. The flowers are slightly necked, pendent, tubular, white, with green tips, hanging from the undersides of the stems. Directions. Other reviews suggest an idiopathic nature to the toxicity, with more than 400 cases reported. Discussing the plant he knew as polygonum in 1655, Matthias Martinius referred to Scribonius Largus (who wrote a list of prescriptions around 47 AD) and gave an alternative etymology, based on γόνος (gonos, 'offspring', 'seed'), the meaning of the name then being the Latin foecundus, i.e. Polygonum multiflorum Thunb. Purported antiaging effects mostly rely on in vitro studies of antioxidant and neuroprotective effects.5, Topical application of P. multiflorum has to induced follicular keratinocyte proliferation in mice.19, 20 The inhibition of tyrosinase activity in mice melanocytes has also been demonstrated,21 and compounds isolated from P. multiflorum roots induced a greater proliferation of dermal papilla cells than minoxidil in an in vitro study.22. Description Polygonatum multiflorum is a rhizomatous perennial that grows up to 3 feet (90 cm) tall and up to 10 inches (25 cm) wide, with alternate leaves on arching stems. Last updated on Dec 12, 2019. Avoid use. P. multiflorum is native to central and southern China and is also distributed in Japan and Taiwan. Embryonic toxicity has been reported. This is especially helpful to older people. (He Shou Wu in Chinese pinyin, hereinafter referred to as HSW) is the root ofPolygonum multiflorum, a member of Polygonaceae. [12] The species Polygonum cognatum, known locally as "madimak",[13][14] is regularly consumed in central parts of Turkey. Habitat: Polygonum multiflorum is widely seen in all parts of China and it is cultivated all around the country. Polygonum L. – knotweed Species: Polygonum multiflorum Thunb. Polygonatum multiflorum. Anti-HIV activities of the compounds isolated from Polygonum cuspidatum and Polygonum multiflorum. Click below on a thumbnail map or name for species profiles. The species is hermaphrodite (has both male and female organs). P. multiflorum is widely used in Chinese medicine; however, adverse event reporting under clinical trial conditions is lacking. Polygonum is a genus in the Polygonaceae family. Common Name: Fo-ti. It is important to fully inform your doctor about the herbal, vitamins, mineral or any other supplements you are taking before any kind of surgery or medical procedure. Clinical trials reporting on efficacy are limited.4, A mixture including he shou wu has been studied for its effects on the glucocorticoid receptor in senile rat thymocytes.15 An effect of emoghrelin, derived from P. multiflorum, stimulated growth hormone in vitro,16 and tetrahydroxystilbene glucoside protected against the thinning of mice derma associated with aging.17 Lifespan and lipid studies of he shou wu in quails have been performed.18, There are no clinical data regarding the use of P. multiflorum for antiaging effects. The plant may also be nephro-, neuro-, and embryotoxic. It is a perennial climbing herb that can grow to 9 m in height. of herb, cover and steep 3-5 minutes. Embryonic toxicity has been reported.53, Case reports are lacking. Several species can be eaten cooked,[11] for example during famines. There have been various opinions about how broadly the genus should be defined. Polygonum multiflorum Thunb belongs to the Polygonaceae family of plants. Polygonum hydropiper is a ANNUAL growing to 0.8 m (2ft 7in). P. multiflorum is used at daily doses of 9 to 15 g of raw herb, but clinical studies are lacking. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. In vitro studies and limited animal data suggest P. multiflorum extracts, tetrahydroxystilbene glucoside and emodin, possess anticancer properties.5, 12, 23, 24 The focus of research into antiapoptotic activity centers on neuroprotection against degenerative disease (see CNS). Clinical trials are lacking to support claims for therapeutic purposes, but topical applications for the treatment of alopecia and a role in neurodegenerative diseases are being investigated. This product may be unsafe when used before surgery or other medical procedures. 10.1 Other Names: 11 Historical Use of Polygonum multiflorum. [6], Many members of the family Polygonaceae that are now placed in separate genera were at one time or other placed in Polygonum, including species of Fagopyrum, Fallopia, Persicaria and Reynoutria,[7] and older sources frequently use much wider definitions of the genus. View abstract. Available for Android and iOS devices. It has been used for thousands of years to promote long life, nourish blood, strengthen bones, tendons and muscles as well as many other purposes. by Subhuti Dharmananda, Ph.D., Director, Institute for Traditional Medicine, Portland, Oregon. Polygonum multiflorum, Helxine multiflorum, Pleuroptterus cordatus, Polygonum convolvulus, Polygonum multiflorus Common Names Chinese Knotweed, Climbing Knotweed, Fo ti, Flowery Knotweed, He-Shou-Wu, Kashuu [7] Origin: China. Latin Name Common Name Habit Height Hardiness Growth Soil Shade Moisture Edible Medicinal Other; Polygonum alaskanum: Alaska Wild Rhubarb: Perennial: 1.8 - LMH: SN: M: 2: 1 : Polygonum alpinum: Alpine Knotweed, Alaska wild rhubarb: Perennial: 1.0: 4-8 LMH: SN: M: 2: 1 Hepatotoxicity has been documented. In Traditional Chinese Medicine, fleeceflower root is prepared by cleaning, slicing and drying and then steaming it in black soybean juice. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. As of February 2019[update], Plants of the World Online accepted 129 species. They have a membranous ochrea (a sheath around the stem nodes). [2], The genus Polygonum was first described by Carl Linnaeus in 1754. .mw-parser-output table.clade{border-spacing:0;margin:0;font-size:100%;line-height:100%;border-collapse:separate;width:auto}.mw-parser-output table.clade table.clade{width:100%;line-height:inherit}.mw-parser-output table.clade td.clade-label{width:0.7em;padding:0 0.15em;vertical-align:bottom;text-align:center;border-left:1px solid;border-bottom:1px solid;white-space:nowrap}.mw-parser-output table.clade td.clade-fixed-width{overflow:hidden;text-overflow:ellipsis}.mw-parser-output table.clade td.clade-fixed-width:hover{overflow:visible}.mw-parser-output table.clade td.clade-label.first{border-left:none;border-right:none}.mw-parser-output table.clade td.clade-label.reverse{border-left:none;border-right:1px solid}.mw-parser-output table.clade td.clade-slabel{padding:0 0.15em;vertical-align:top;text-align:center;border-left:1px solid;white-space:nowrap}.mw-parser-output table.clade td.clade-slabel:hover{overflow:visible}.mw-parser-output table.clade td.clade-slabel.last{border-left:none;border-right:none}.mw-parser-output table.clade td.clade-slabel.reverse{border-left:none;border-right:1px solid}.mw-parser-output table.clade td.clade-bar{vertical-align:middle;text-align:left;padding:0 0.5em;position:relative}.mw-parser-output table.clade td.clade-bar.reverse{text-align:right;position:relative}.mw-parser-output table.clade td.clade-leaf{border:0;padding:0;text-align:left}.mw-parser-output table.clade td.clade-leafR{border:0;padding:0;text-align:right}.mw-parser-output table.clade td.clade-leaf.reverse{text-align:right}.mw-parser-output table.clade:hover span.linkA{background-color:yellow}.mw-parser-output table.clade:hover span.linkB{background-color:green}, Polygonum ciliinode (syn. 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polygonum multiflorum common name

Fo-ti is an herb. The processed root has been used to lower cholesterol levels in Traditional Chinese Medicine. It cannot grow in the shade. We comply with the HONcode standard for trustworthy health information -. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this product. Free and Open Access to Biodiversity Data. 'fecund', 'with many offspring'. [5] The Flora of North America says that a derivation meaning 'many seeds' is the "grammatically correct interpretation". Medically reviewed by Drugs.com. Planta Med 2010;76(9):889-92. Polygonum bohemicum — ID 66299 Symbol Key POBO10 Common Name Bohemian knotweed Family Polygonaceae Category Dicot Division Magnoliophyta US Nativity Cultivated, or not in the U.S. US/NA Plant Yes State Distribution N/A Growth Habit N/A … Select one or more newsletters to continue. Reynoutria multiflorum var. In The Man Who Laughs Victor Hugo wrote of the Comprachicos (child-buyers) who created artificial dwarfs, formed "by anointing babies' spines with the grease of bats, moles and dormice" and using drugs such as "dwarf elder, knotgrass, and daisy juice". The genus primarily grows in northern temperate regions. The leaves are arranged alternately, usually less than 2 cm (0.8 in) long, with a length greater than the width. For example, buckwheat (Fagopyrum esculentum) has sometimes been included in the genus as Polygonum fagopyrum. A standard dose in the Chinese Pharmacopoeia is 3 to 12 g/day.50, P. multiflorum is usually used in combination with other traditional products.4, 5, Avoid use. In the Middle English glossary of herbs Alphita (c. 1400–1425), it was known as ars-smerte. – tuber fleeceflower Species on this page ( A = names approved by most authorities, s = approved as synonyms) : Polygonum affine D. Don s -> Fallopia aubertii (L. Henry) Holub A; Polygonum amphibium L. -> Persicaria amphibia (L.) Gray; Polygonum amplexicaule D. Don; Polygonum aubertii L. Henry s-> Fallopia aubertii (L. Henry) Holub A hypoleucum It is native to Central and southern China. When the genus is defined narrowly, Polygonum species are annual or perennial herbaceous plants, rarely shrubby, with much branched stems. Scientific Name(s): Polygonum multiflorum Thunb.Common Name(s): Chinese cornbind, Climbing knotweed, Flowery knotweed, Fo-ti, Heshouwu, Radix Polygoni multiflori, Tuber fleeceflower. Fallopia multiflora (Thunb.) Of the 217 supplement products implicated in liver injury, fo-ti was among the 22% (116) of the single-ingredient products.55, Reviews of the toxic effects, possibly dose- and duration-related, of P. multiflorum on the liver have been published. WHAT'S IN AN HERB NAME? It is probably best known for it’s ability to turn grey hair dark again. Prepare as a tea or tonic, or as directed by a physician. Emodin has demonstrated inhibitory effects on vasodilation in isolated rat aortas.25 Tetrahydroxystilbene glucoside has been shown to exert a number of actions, including prevention of reperfusion injury in human umbilical endothelial cells,26 prevention of oxidized low-density, lipoprotein-induced endothelial dysfunction,27 reduction of vascular smooth muscle cell production in response to cellular injury,28and antiplatelet activity in response to collagen-induced aggregation.29. A number of species that had been included in Polygonum have been moved into several other genera, including Bistorta, Fagopyrum, Fallopia, Koenigia, Persicaria and Reynoutria. He Shou Wu is a Chinese herbal medicine, derived from the Polygonum multiflorum Thunb plant ().. The roots are the main plant part of interest and are harvested and dried in autumn when they are 3 to 4 years of age, but the stems and leaves are also used. Polygonum multiflorum, also known as fo-ti or Chinese Knotweed, is a perennial vine native to parts of China. Liver transplant was also more frequent with toxicity from non-bodybuilding supplements (13%) than with conventional medications (3%) (P<0.001). Overall, the number of severe liver injury cases was significantly higher from supplements than conventional medications (P=0.02). This information is not specific medical advice and does not replace information you receive from your health care provider. The species Polygonatum multiflorum is often called the Common Solomon's Seal, native to Europe it has been long cultivated for its use as a medicinal herb. Suitable pH: acid, neutral and basic (alkaline) soils. Ho-shou-wu (pinyin: heshouwu) is derived from the roots of Polygonum multiflorum.The herb was first recorded (1,2,16) in the Ri Huazi Bencao (Tang Dynasty, 713 A.D.) and then incorporated into the well-known Kaibao Bencao (Song Dynasty; 973 A.D.). There are no clinical data regarding the use of P. multiflorum in cardiovascular-related disorders. Common Name: He Shou Wu. Care should be taken not to confuse Polygonum with Polygonatum – an entirely different genus of plants. Evidence of hepatic injury in humans exists; consider P. multiflorum and its extracts hepatotoxic. The flowers are slightly necked, pendent, tubular, white, with green tips, hanging from the undersides of the stems. Directions. Other reviews suggest an idiopathic nature to the toxicity, with more than 400 cases reported. Discussing the plant he knew as polygonum in 1655, Matthias Martinius referred to Scribonius Largus (who wrote a list of prescriptions around 47 AD) and gave an alternative etymology, based on γόνος (gonos, 'offspring', 'seed'), the meaning of the name then being the Latin foecundus, i.e. Polygonum multiflorum Thunb. Purported antiaging effects mostly rely on in vitro studies of antioxidant and neuroprotective effects.5, Topical application of P. multiflorum has to induced follicular keratinocyte proliferation in mice.19, 20 The inhibition of tyrosinase activity in mice melanocytes has also been demonstrated,21 and compounds isolated from P. multiflorum roots induced a greater proliferation of dermal papilla cells than minoxidil in an in vitro study.22. Description Polygonatum multiflorum is a rhizomatous perennial that grows up to 3 feet (90 cm) tall and up to 10 inches (25 cm) wide, with alternate leaves on arching stems. Last updated on Dec 12, 2019. Avoid use. P. multiflorum is native to central and southern China and is also distributed in Japan and Taiwan. Embryonic toxicity has been reported. This is especially helpful to older people. (He Shou Wu in Chinese pinyin, hereinafter referred to as HSW) is the root ofPolygonum multiflorum, a member of Polygonaceae. [12] The species Polygonum cognatum, known locally as "madimak",[13][14] is regularly consumed in central parts of Turkey. Habitat: Polygonum multiflorum is widely seen in all parts of China and it is cultivated all around the country. Polygonum L. – knotweed Species: Polygonum multiflorum Thunb. Polygonatum multiflorum. Anti-HIV activities of the compounds isolated from Polygonum cuspidatum and Polygonum multiflorum. Click below on a thumbnail map or name for species profiles. The species is hermaphrodite (has both male and female organs). P. multiflorum is widely used in Chinese medicine; however, adverse event reporting under clinical trial conditions is lacking. Polygonum is a genus in the Polygonaceae family. Common Name: Fo-ti. It is important to fully inform your doctor about the herbal, vitamins, mineral or any other supplements you are taking before any kind of surgery or medical procedure. Clinical trials reporting on efficacy are limited.4, A mixture including he shou wu has been studied for its effects on the glucocorticoid receptor in senile rat thymocytes.15 An effect of emoghrelin, derived from P. multiflorum, stimulated growth hormone in vitro,16 and tetrahydroxystilbene glucoside protected against the thinning of mice derma associated with aging.17 Lifespan and lipid studies of he shou wu in quails have been performed.18, There are no clinical data regarding the use of P. multiflorum for antiaging effects. The plant may also be nephro-, neuro-, and embryotoxic. It is a perennial climbing herb that can grow to 9 m in height. of herb, cover and steep 3-5 minutes. Embryonic toxicity has been reported.53, Case reports are lacking. Several species can be eaten cooked,[11] for example during famines. There have been various opinions about how broadly the genus should be defined. Polygonum multiflorum Thunb belongs to the Polygonaceae family of plants. Polygonum hydropiper is a ANNUAL growing to 0.8 m (2ft 7in). P. multiflorum is used at daily doses of 9 to 15 g of raw herb, but clinical studies are lacking. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. In vitro studies and limited animal data suggest P. multiflorum extracts, tetrahydroxystilbene glucoside and emodin, possess anticancer properties.5, 12, 23, 24 The focus of research into antiapoptotic activity centers on neuroprotection against degenerative disease (see CNS). Clinical trials are lacking to support claims for therapeutic purposes, but topical applications for the treatment of alopecia and a role in neurodegenerative diseases are being investigated. This product may be unsafe when used before surgery or other medical procedures. 10.1 Other Names: 11 Historical Use of Polygonum multiflorum. [6], Many members of the family Polygonaceae that are now placed in separate genera were at one time or other placed in Polygonum, including species of Fagopyrum, Fallopia, Persicaria and Reynoutria,[7] and older sources frequently use much wider definitions of the genus. View abstract. Available for Android and iOS devices. It has been used for thousands of years to promote long life, nourish blood, strengthen bones, tendons and muscles as well as many other purposes. by Subhuti Dharmananda, Ph.D., Director, Institute for Traditional Medicine, Portland, Oregon. Polygonum multiflorum, Helxine multiflorum, Pleuroptterus cordatus, Polygonum convolvulus, Polygonum multiflorus Common Names Chinese Knotweed, Climbing Knotweed, Fo ti, Flowery Knotweed, He-Shou-Wu, Kashuu [7] Origin: China. Latin Name Common Name Habit Height Hardiness Growth Soil Shade Moisture Edible Medicinal Other; Polygonum alaskanum: Alaska Wild Rhubarb: Perennial: 1.8 - LMH: SN: M: 2: 1 : Polygonum alpinum: Alpine Knotweed, Alaska wild rhubarb: Perennial: 1.0: 4-8 LMH: SN: M: 2: 1 Hepatotoxicity has been documented. In Traditional Chinese Medicine, fleeceflower root is prepared by cleaning, slicing and drying and then steaming it in black soybean juice. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. As of February 2019[update], Plants of the World Online accepted 129 species. They have a membranous ochrea (a sheath around the stem nodes). [2], The genus Polygonum was first described by Carl Linnaeus in 1754. .mw-parser-output table.clade{border-spacing:0;margin:0;font-size:100%;line-height:100%;border-collapse:separate;width:auto}.mw-parser-output table.clade table.clade{width:100%;line-height:inherit}.mw-parser-output table.clade td.clade-label{width:0.7em;padding:0 0.15em;vertical-align:bottom;text-align:center;border-left:1px solid;border-bottom:1px solid;white-space:nowrap}.mw-parser-output table.clade td.clade-fixed-width{overflow:hidden;text-overflow:ellipsis}.mw-parser-output table.clade td.clade-fixed-width:hover{overflow:visible}.mw-parser-output table.clade td.clade-label.first{border-left:none;border-right:none}.mw-parser-output table.clade td.clade-label.reverse{border-left:none;border-right:1px solid}.mw-parser-output table.clade td.clade-slabel{padding:0 0.15em;vertical-align:top;text-align:center;border-left:1px solid;white-space:nowrap}.mw-parser-output table.clade td.clade-slabel:hover{overflow:visible}.mw-parser-output table.clade td.clade-slabel.last{border-left:none;border-right:none}.mw-parser-output table.clade td.clade-slabel.reverse{border-left:none;border-right:1px solid}.mw-parser-output table.clade td.clade-bar{vertical-align:middle;text-align:left;padding:0 0.5em;position:relative}.mw-parser-output table.clade td.clade-bar.reverse{text-align:right;position:relative}.mw-parser-output table.clade td.clade-leaf{border:0;padding:0;text-align:left}.mw-parser-output table.clade td.clade-leafR{border:0;padding:0;text-align:right}.mw-parser-output table.clade td.clade-leaf.reverse{text-align:right}.mw-parser-output table.clade:hover span.linkA{background-color:yellow}.mw-parser-output table.clade:hover span.linkB{background-color:green}, Polygonum ciliinode (syn. 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